Boston College
| Player | Injury | Status | Details |
|---|---|---|---|
| Evan Dickens (RB) | Knee | Out | |
| Onye Nwosisi (DL) | Undisclosed | Out | |
| Reed Swanson (WR) | Undisclosed | Out | |
| Sedric Addison (RB) | Undisclosed | Out |
Clemson
| Player | Injury | Status | Details |
|---|---|---|---|
| Cole Turner (WR) | Personal | Out | |
| Corian Gipson (CB) | Knee | Out | |
| David Eziomume (RB) | Leg | Out | |
| Elyjah Thurmon (OL) | Undisclosed | Out | |
| Gideon Davidson (RB) | Ankle | Out | |
| Harris Sewell (OL) | Undisclosed | Out | |
| Peyton Streko (RB) | Undisclosed | Out | |
| Tyler Brown (WR) | Undisclosed | Out |
Duke
| Player | Injury | Status | Details |
|---|---|---|---|
| Cosme Salas (PK) | Undisclosed | Out | |
| Jamien Little (WR) | Undisclosed | Out | |
| Kavon Simmons (WR) | Undisclosed | Out | |
| Kimari Robinson (CB) | Undisclosed | Out | |
| Qeanu Johnson (WR) | Undisclosed | Out |
FSU
| Player | Injury | Status | Details |
|---|---|---|---|
| Blake Nichelson (LB) | Undisclosed | Out | |
| Conor McAneney (PK) | Undisclosed | Out | |
| Daylen Green (LB) | Undisclosed | Out | |
| Duce Robinson (WR) | Knee | Out | |
| Izayia Williams (LB) | Undisclosed | Out | |
| K.J. Kirkland (DB) | Undisclosed | Questionable | |
| Kevin Wynn (DL) | Undisclosed | Out | |
| Ousmane Kromah (RB) | Ankle | Out | |
| Quindarrius Jones (DB) | Undisclosed | Out | |
| Samuel Singleton (RB) | Lower Body | Out |
Georgia Tech
| Player | Injury | Status | Details |
|---|---|---|---|
| A.J. Hoffler (DE) | Undisclosed | Out | |
| Ethan Mackenny (OL) | Undisclosed | Out | |
| Kelvin Hill (CB) | Undisclosed | Out | |
| Kentrell Davis (WR) | Undisclosed | Out | |
| Malachi Hosley (RB) | Undisclosed | Out | |
| Markell Samuel (OL) | Undisclosed | Out | |
| Rahkeem Smith (WR) | Undisclosed | Out | |
| Savion Riley (S) | Undisclosed | Out | |
| Shane Marshall (RB) | Undisclosed | Questionable | |
| Shymeik Jones (DT) | Undisclosed | Out |
Louisville
| Player | Injury | Status | Details |
|---|---|---|---|
| Antonio Watts (DB) | Knee | Out | |
| Anwar O'Neal (OL) | Undisclosed | Out | |
| Hamilton Atkins (TE) | Undisclosed | Out | |
| Isaac Brown (RB) | Undisclosed | Questionable | |
| Jacob Baker (P) | Knee | Out | |
| Kris Hughes (WR) | Lower Body | Out | |
| Lawayne McCoy (WR) | Knee | Out | |
| Payton Cook (WR) | Undisclosed | Out |
Miami
| Player | Injury | Status | Details |
|---|---|---|---|
| CharMar Brown (RB) | Lower Body | Out | |
| Joshua Moore (WR) | Upper Body | Out | |
| Luka Gilbert (TE) | Undisclosed | Out | |
| Malachi Toney (WR) | Ankle | Out |
UNC
| Player | Injury | Status | Details |
|---|---|---|---|
| Keeyun Chapman (WR) | Not Injury Related | Out |
Notre Dame
| Player | Injury | Status | Details |
|---|---|---|---|
| Brauntae Johnson (S) | Foot | Out | |
| Cooper Flanagan (TE) | Undisclosed | Questionable | |
| DJ McKinney (CB) | Ankle | Out | |
| Drayk Bowen (LB) | Ankle | Out | |
| James Flanigan (TE) | Undisclosed | Questionable | |
| Kyngstonn Viliamu-Asa (LB) | Undisclosed | Out | |
| Micah Gilbert (WR) | Ankle | Questionable | |
| Quincy Porter (WR) | Kneecap | Out |
Pittsburgh
| Player | Injury | Status | Details |
|---|---|---|---|
| Cameron Lindsey (LB) | Undisclosed | Out | |
| Elijah Lagg (TE) | Undisclosed | Questionable | |
| Ja'Kyrian Turner (RB) | Lower Body | Questionable | |
| Malik Knight (WR) | Undisclosed | Questionable | |
| Mason Heintschel (QB) | Knee | Out | |
| Max Hunt (TE) | Undisclosed | Questionable | |
| Rodney Dunbar (WR) | Undisclosed | Questionable | |
| Tyreek Robinson (WR) | Undisclosed | Questionable |
NC State
| Player | Injury | Status | Details |
|---|---|---|---|
| Ian Flynt (TE) | Undisclosed | Out | |
| Nick Konieczynski (PK) | Undisclosed | Out | |
| Preston Douglas (TE) | Undisclosed | Out | |
| Teague Andersen (OL) | Undisclosed | Questionable | |
| Teddy Hoffmann (WR) | Suspension | Out | |
| Tristan Teasdell (S) | Undisclosed | Out | |
| Vander Ploog (TE) | Undisclosed | Out | |
| Will Wilson (QB) | Undisclosed | Probable | |
| Yousef Mugharbil (OL) | Undisclosed | Out |
Syracuse
| Player | Injury | Status | Details |
|---|---|---|---|
| Amari Odom (QB) | Shoulder | Out | |
| Darien Williams (WR) | Undisclosed | Out | |
| Dillan Fontus (DL) | Undisclosed | Probable | |
| Malachi Nelson (QB) | Ankle | Out | |
| Terrell Wilfong (WR) | Undisclosed | Out | |
| Tunmise Adeleye (DL) | Undisclosed | Probable |
Virginia
| Player | Injury | Status | Details |
|---|---|---|---|
| Brandyn Hillman (S) | Undisclosed | Out | |
| Devon Baxter (DE) | Shoulder | Out | |
| Ethan Minter (S) | Undisclosed | Out | |
| Jack Stevens (RB) | Undisclosed | Questionable | |
| Jason Hammond (DT) | Undisclosed | Out | |
| Jekail Middlebrook (RB) | Knee | Questionable | |
| Justin Zames (TE) | Undisclosed | Questionable | |
| Kameron Courtney (WR) | Ankle | Questionable | |
| Noah Vaughn (RB) | Undisclosed | Questionable | |
| Omillio Agard (CB) | Knee | Out | |
| Rico Flores (WR) | Knee | Out | |
| Tim Hamann (PK) | Undisclosed | Questionable |
Virginia Tech
| Player | Injury | Status | Details |
|---|---|---|---|
| Luke Stuewe (WR) | Undisclosed | Out | |
| Shamarius Peterkin (WR) | Undisclosed | Out | |
| Thomas Williams (CB) | Undisclosed | Out |