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Boston College
| Player | Injury | Status | Details |
|---|---|---|---|
| Bryce Dopson (WR) | Undisclosed | Questionable | |
| Kaelan Chudzinski (TE) | Achilles | Out |
Clemson
| Player | Injury | Status | Details |
|---|---|---|---|
| Cole Turner (WR) | Personal | Questionable | |
| Jay Haynes (RB) | Undisclosed | Questionable | |
| Peyton Streko (RB) | Undisclosed | Doubtful | |
| T.J. Moore (WR) | Undisclosed | Probable |
FSU
| Player | Injury | Status | Details |
|---|---|---|---|
| Devin Carter (WR) | Back | Out |
Louisville
| Player | Injury | Status | Details |
|---|---|---|---|
| Jacob Baker (P) | Knee | Out | |
| Kris Hughes (WR) | Lower Body | Out | |
| Marquise Davis (RB) | Lower Body | Questionable | |
| Montavin Quisenberry (WR) | Lower Body | Out |
Miami
| Player | Injury | Status | Details |
|---|---|---|---|
| Jordan Lyle (RB) | Not Injury Related | Questionable | |
| Luka Gilbert (TE) | Undisclosed | Out |
UNC
| Player | Injury | Status | Details |
|---|---|---|---|
| Benjamin Hall (RB) | Undisclosed | Probable | |
| Jaxxon Warren (TE) | Undisclosed | Out | |
| Jordan Washington (TE) | Undisclosed | Questionable |
Notre Dame
| Player | Injury | Status | Details |
|---|---|---|---|
| Brayden Robinson (WR) | Knee | Questionable | |
| Elijah Burress (WR) | Hamstring | Questionable | |
| Quincy Porter (WR) | Kneecap | Questionable |
NC State
| Player | Injury | Status | Details |
|---|---|---|---|
| Gus Ritchey (TE) | Undisclosed | Out | |
| Teddy Hoffmann (WR) | Suspension | Out | |
| Tyreek Copper (WR) | Undisclosed | Questionable |
Syracuse
| Player | Injury | Status | Details |
|---|---|---|---|
| Cole Weaver (WR) | Undisclosed | Probable | |
| Terrell Wilfong (WR) | Collarbone | Out |
Virginia
| Player | Injury | Status | Details |
|---|---|---|---|
| Dillon Newton-Short (WR) | Hamstring | Questionable | |
| Isaiah Robinson (WR) | Undisclosed | Questionable | |
| Jack Stevens (RB) | Undisclosed | Questionable | |
| Kam Robinson (LB) | Undisclosed | Out | |
| Lukas Ungar (TE) | Undisclosed | Questionable | |
| Solomon Beebe (RB) | Suspension | Out | |
| Tim Hamann (PK) | Undisclosed | Questionable | |
| Triston Ward (WR) | Undisclosed | Questionable |
Virginia Tech
| Player | Injury | Status | Details |
|---|---|---|---|
| Bill Davis (RB) | Undisclosed | Questionable | |
| Joseph Hobbs (WR) | Undisclosed | Questionable | |
| Luke Stuewe (WR) | Undisclosed | Questionable | |
| Shamarius Peterkin (WR) | Undisclosed | Questionable | |
| Takye Heath (WR) | Undisclosed | Questionable |
