The Cardinal put up a tough fight in the season opener, but eventually fell to the visiting Horned Frogs, 34-27. Stanford took a 24-20 lead with 6:57 left in the game but could not hold on. Wide receiver Elic Ayomanor had seven receptions for 102 yards. Quarterback Ashton Daniels finished the game with 163 passing yards, 83 rushing yards, and a passing touchdown. Backup quarterback Justin Lamson threw a 2-yard touchdown and ran in a 1-yard touchdown.