North Carolina A&T vs. Duke: The Duke Blue Devils won their home opener 45-17 over North Carolina A&T. Duke only possessed the ball for 7:36 in the first half, but took a 21-14 lead into halftime. The Blue Devils then went off in the third quarter, outsourcing the Aggies 21-3 in the third quarter. Running back Mataeo Durant scored three touchdowns in a game for the second time in two games in the 2021 season. Durant also totaled 69 total yards. Quarterback Gunnar Holmberg passed for 270 yards, ran for 30 yards, and scored two touchdowns on the ground. Wide Receiver Jake Bobo caught nine passes for 90 yards.